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-   -   The Science of Nutrition (https://www.miataturbo.net/insert-bs-here-4/science-nutrition-75333/)

Braineack 02-04-2014 01:26 PM

1 Attachment(s)
I went vegan* last night:

https://www.miataturbo.net/attachmen...ine=1391538378

Mushroom balls, over squash, with red pepper pesto.


*an egg was used as binder.

Hinano 02-04-2014 03:10 PM


Originally Posted by Joe Perez (Post 1095985)
"No MSG"
Why?

Read up on it. Different people get different side effects.

I get dehydrated, headaches, and even twitches if I have allot. It's not good for you. Even Panda Express has banned its use.

Have you noticed feeling like you cant get enough water after eating Chinese? Or many Japanese foods for that matter. (Japan invented MSG, it's called Ajinomoto) Or mild headaches?... MSG for sure.

y8s 02-04-2014 05:14 PM

If you love Doritos... you love MSG.

I don't have a sensitivity to it. Unless you count enjoyment as a sensitivity. Mcdonalds used to use it too.

Braineack 02-04-2014 05:35 PM

MSG is good. The Stigma is stupid.

Hinano 02-04-2014 06:30 PM


Originally Posted by Braineack (Post 1098823)
MSG is good. The Stigma is stupid.

Try it yourself. Buy some MSG in powder form. Make a nice vegetable soup with plenty of this so called good MSG. Put extra because it's "good."

I bet you you will get sweats and headache. I would know as it's night and day form me.

Try it and get back to us.

nitrodann 02-04-2014 07:22 PM

99% of people who say this have never done back to back blind testing.

This is exactly like all the bullshit about kids going hyper on sugar.

Dann

y8s 02-04-2014 09:15 PM

Wikipedia entry on MSG cites several studies that were done that all fail to link any symptoms to consumption.

I hear vaccines cause autism because a playboy bunny said so.

Joe Perez 02-04-2014 10:34 PM


Originally Posted by Hinano (Post 1098756)
Read up on it. Different people get different side effects.

After you posted your last response, I did go and do quite a bit of reading up on the subject.

Aside from a few blog entries which I would charitably describe as hysterical and ill-informed, pretty much all of the "hard" data (eg: peer-reviewed medical and academic journals), tend to fall into one of two schools of thought:

1: That the myth of MSG having any harmful effects at all is just that, a myth, and that whatever physical ailments might manifest themselves in a person who has just consumed a cheap Chinese meal tend to fall along a spectrum which ranges from psychosomatic at one end, to "you dummy, you just ate a huge plate of salty, sugary, carb-laden, fried food. What do you expect?" at the other.

2: An acknowledgement that some or all of the symptoms which you describe below do in fact occur, but only in a small percentage of the population, and that the effects of the consumption of large amounts of MSG tend to be acute in nature (eg: occurring quickly after consumption and later dissipating completely with no lasting ill-effect) rather than chronic (having long-term health consequences.)


Your admonition wasn't really clear on the nature of your objection to MSG, and I was much more curious to learn of the basis for your objection to it than to simply hear a list of commonly-alleged symptoms.


For instance, one fairly recent study conducted by the Lab de Desarrollo-Envejecimiento, Enfermedades Neurodegenerativas in Guadalajara, Mexico demonstrated a strong positive correlation between high doses of MSG and neural necrosis in lab rats. The problem here is that this particular study involved the injection of MSG directly into the brain, completely bypassing the metabolic decomposition which naturally occurs in the gastric tract.


I have also read a few non-scientific papers which claim to observe a link between MSG intake and obesity as a function of MSG causing disorders related to insulin production in the body (example). Well, I've disproven this to my own satisfaction simply by performing blood glucose tests before and after consuming a cheap Chinese meal containing a large amount of MSG. This is nothing more than mistaken causality. Of course there's a correlation between obesity and the consumption of large amounts of MSG. By definition, a majority of people who are regularly consuming large amounts of MSG are also consuming large amounts of calories!

Joe Perez 02-04-2014 10:34 PM


Originally Posted by Hinano (Post 1098756)
I get dehydrated, headaches, and even twitches if I have allot.

I don't doubt that you do. However this does not justify an unqualified blanket statement that "MSG is bad."

There are many different foods and chemicals to which some small percentage of the populace react adversely. Some people are lactose-intolerant. Some are allergic to shellfish. Or peanuts. Or eggs. Or strawberries. Or the pollen of the oak tree.

Personally, I am severely allergic to cats (specifically, the protein Fel-d-1 which is present in their saliva and sebaceous glands.) That doesn't mean that cats are evil and should be avoided, merely that I, along with a small minority of the population, cannot tolerate prolonged exposure to them.

My own mother experiences a severe dermal reaction to prolonged contact with nickel-bearing metal alloys such as stainless steel, meaning that she cannot wear most wristwatches, as they tend to have stainless backplates. But I would never post a blanket statement that "stainless steel is bad for you and you must avoid contact with it!"


Just because a small number of people react adversely to exposure to a certain substance does not in any way justify claims that said substance is "bad" in a broad context.

Joe Perez 02-04-2014 10:35 PM


Originally Posted by Hinano (Post 1098756)
Have you noticed feeling like you cant get enough water after eating Chinese? Or many Japanese foods for that matter. (Japan invented MSG, it's called Ajinomoto) Or mild headaches?... MSG for sure.

No, I have not noticed these things. I can wolf down a plate of the cheapest late-night midtown Chinese takeout imaginable (and often have in the past), and I suffer from none of the effects which you describe above.

By the same token, I assume that you can cuddle with a kitty without your eyes watering and your skin itching.

Hinano 02-05-2014 01:54 AM

I've read a study or two couple years ago but I have enough experience for me to decide on my own.

I never "knew" about MSG until a few years ago. When I first started using it, I would always make a huge pot veggie soup for me and friends with MSG. I would put in allot because it made it taste good. I always wondered why I would sweat so much and have headaches and be so damn thirsty after a huge bowl of soup. It might be unbelievable but I actually thought that all the veggies was some how "clearing" my system up but it was not that, it was the MSG. I also have friends who have this same issue of dehydration and or headaches. I and friends would know since we do endurance workouts too, we are pretty in tune with our bodies.

I don't need a study to tell me what MSG is doing to me. Perhaps some are more susceptible to the effects but maybe the amount you are eating is small enough where you don't really notice the effects. Or maybe your local chinese place doesn't use MSG at all. You should give them a call and ask.

Also, I still recommend that you do a test yourself. Try buy some MSG and eat whatever amount you think is still safe and see what happens. I do commend you for your determination to find truth.

Braineack 02-05-2014 07:55 AM


Originally Posted by Hinano (Post 1098846)
Try it yourself. Buy some MSG in powder form. Make a nice vegetable soup with plenty of this so called good MSG. Put extra because it's "good."

I bet what happens is I have an incredible tasting soup because it's a much better flavor booster than salt.

I'm actually making chicken soup tonight--true story.



I bet you you will get sweats and headache. I would know as it's night and day form me.
I've seen tests done in this manner. A group of people were served the same dish. Half got it with MSG, the other half salt.

They were told after consumption and asked if they felt any side effects after time had elapsed. More people from the group that consumed salt complained of all the symptoms that MSG causes...the test wasn't scientific, but it showed the power of suggestion once they were told they might have consumed MSG.

If you have a sensitivity to it, not everyone else in the world does. That's like saying cats are universally bad and should be avoided because they cause a histamatic reaction to some inferior humans. Or that we should all eat gluten free because some vegan lesbian hipster who uses abortion as birth control thinks it's a good idea that everyone live exactly like her while telling everyone to be individuals and have their own identity and uniqueness.

Hinano 02-05-2014 04:38 PM


Originally Posted by Braineack (Post 1099012)

I'm actually making chicken soup tonight--true story.

How did it go and exactly how much MSG did you use?


Originally Posted by Braineack (Post 1099012)
Or that we should all eat gluten free because some vegan lesbian hipster who uses abortion as birth control thinks it's a good idea that everyone live exactly like her while telling everyone to be individuals and have their own identity and uniqueness.

Oooookay.... LOL

I don't think people who are pro choice on abortion believe everyone should do it. I think it's about choice. Also, society decides morals and ethics.

While I do eat meat, I could say that our individual freedom of eating meat is contributing immensely to suffering and abuse of animals and destroying this planet due to the environmental impact of animal food production which means that your selfish idea of individual freedom is taking away from the livelihoods of all those around the world who cannot afford to deal with climate change and may lose everything they have and or die. To be honest, there is quite a strong case to stop eating meat all together if not at least creating a maximum intake per person for it. Not that I think it is feasible.

If I may also just add, I actually don't think we will stop climate change so although reducing pollution is very important, I think spending allot of energy on bringing up the living standards of those all over the world will be the best way to mitigate the impacts of climate change.

Joe Perez 02-06-2014 12:24 PM

2 Attachment(s)
Stepped on the scale this morning and it read 199.6. That's a milestone for me, and it reinforces my conviction that I've made the right decision to shift from a high-calorie / low-carb diet towards one favoring more moderate caloric intake without being too particular about the specific form that those calories take (eg: not shunning processed grains, starches and sugars entirely.) That's roughly 17 lbs of mostly fat gone in exactly one month to the day since I started this test.


And I'm not kidding about this being a Chinese Takeout diet. With the exception of those weekend evenings spent up in the mountains of late, my dinners have been consisting of nothing but dishes from Precious, such as scallops with broccoli & bean sprouts in hot garlic sauce, with a generous pile of steamed brown rice:

https://www.miataturbo.net/attachmen...1&d=1391707062


I'd previously claimed that once I got below 200 I was going to give the high-fat / low-carb plan another try, but I'm going to stick with this scheme for a while longer and see where it goes. I'm still above the theoretical "ideal" weight for my height and build I'm getting good results without feeling like I'm depriving myself of anything, and my overall health / energy also seems to be doing just fine.

y8s 02-06-2014 02:08 PM


Originally Posted by Joe Perez (Post 1099654)
That's roughly 17 lbs of mostly fat gone

are you measuring your body fat %?

Joe Perez 02-06-2014 02:40 PM


Originally Posted by y8s (Post 1099713)
are you measuring your body fat %?

No, just making subjective estimates based upon pants fit, visual observation, and the fact that my physical strength is not decreasing.

mgeoffriau 02-06-2014 02:42 PM

Joe Perez, the human DEXA scanner.

Braineack 02-06-2014 03:15 PM

I use the depth of my belly button as a gauge...true story.

y8s 02-06-2014 04:35 PM


Originally Posted by Joe Perez (Post 1099729)
No, just making subjective estimates based upon pants fit, visual observation, and the fact that my physical strength is not decreasing.

Sounds scientifish. Just get the damn scale I linked on amazon. At least it will give you consistenly wrong numbers. FWIW I am at 20% BF. I'd like to be at fifteen. I have a 2.5 pack.


Originally Posted by mgeoffriau (Post 1099731)
Joe Perez, the human DEXA scanner.

I'd trust his pincers to be calibrated within a few ten thou.


Originally Posted by Braineack (Post 1099746)
I use the depth of my belly button as a gauge...true story.

You can weigh the lint and increase accuracy.

Joe Perez 02-06-2014 08:08 PM


Originally Posted by y8s (Post 1099768)
Sounds scientifish. Just get the damn scale I linked on amazon. At least it will give you consistenly wrong numbers.

Huh? If you mean the one in post #167, I'm not sure I see the point. It doesn't really look much different from the one I use right now.


EDIT: I didn't mean for that to sound snide- if I'm missing something, please educate me.

Joe Perez 02-06-2014 08:35 PM


Originally Posted by Hinano (Post 1098978)
I've read a study or two couple years ago but I have enough experience for me to decide on my own.

This seems like a somewhat closed-minded perspective to me.

I convinced myself that the MSG Myth was just that years ago, though admittedly with little hard science to support that viewpoint. Of late, you've had me doing a lot of searching on the topic, and what I'm finding is interesting.

Among "trustworthy" sources (eg: those involving proper control / blinding techniques, those published in peer-reviewed journals or as academic theses, and not coming from laypersons who have an obvious financial motivation such as the sale of books, herbal remedies, etc) 100% of the material which I have found completely refutes the idea that MSG consumption leads to long-term negative health consequences in humans, and fairly little of it even acknowledges that MSG, specifically, is physiologically correlated with acute, short-term symptoms of the sort you describe.


A few abstracts:


Because glutamate is one of the most intensely studied food ingredients in the food supply and has been found safe, the Joint Expert Committee on Food Additives of the United Nations Food and Agriculture Organization and World Health Organization placed it in the safest category for food additives. Despite a widespread belief that glutamate can elicit asthma, migraine headache and Chinese Restaurant Syndrome (CRS), there are no consistent clinical data to support this claim. In addition, findings from the literature indicate that there is no consistent evidence to suggest that individuals may be uniquely sensitive to glutamate.

Glutamate. Its applications in food and contribution to health


---

Since the first description of the 'Monosodium glutamate symptom complex', originally described in 1968 as the 'Chinese restaurant syndrome', a number of anecdotal reports and small clinical studies of variable quality have attributed a variety of symptoms to the dietary ingestion of MSG.
(...)
Despite concerns raised by early reports, decades of research have failed to demonstrate a clear and consistent relationship between MSG ingestion and the development of these conditions.

Monosodium glutamate []allergy’: menace or myth? - Williams - 2009 - Clinical & Experimental Allergy - Wiley Online Library


---


Since the first report of the so-called Chinese restaurant syndrome 40 years ago, clinical trials have failed to identify a consistent relationship between the consumption of MSG and the constellation of symptoms that comprise the syndrome. Furthermore, MSG has been described as a trigger for asthma and migraine headache exacerbations, but there are no consistent data to support this relationship. Although there have been reports of an MSG-sensitive subset of the population, this has not been demonstrated in placebo-controlled trials.
(...)
Despite a widespread belief that MSG can elicit a headache, among other symptoms, there are no consistent clinical data to support this claim. Findings from the literature indicate that there is no consistent evidence to suggest that individuals may be uniquely sensitive to MSG. Nurse practitioners should therefore concentrate their efforts on advising patients of the nutritional pitfalls of some Chinese restaurant meals and to seek more consistently documented etiologies for symptoms such as headache, xerostomia, or flushing.

Reconsidering the effects of monosodiu... [J Am Acad Nurse Pract. 2006] - PubMed - NCBI


---

Monosodium glutamate (MSG) has a long history of use in foods as a flavor enhancer. In the United States, the Food and Drug Administration has classified MSG as generally recognized as safe (GRAS). Nevertheless, an ongoing debate exists concerning whether MSG causes any of the alleged reactions. A complex of symptoms after ingestion of a Chinese meal was first described in 1968. MSG was suggested to trigger these symptoms, which were referred to collectively as Chinese Restaurant Syndrome. Numerous reports, most of them anecdotal, were published after the original observation. Since then, clinical studies have been performed by many groups, with varying degrees of rigor in experimental design ranging from uncontrolled open challenges to double-blind, placebo controlled (DBPC) studies. Challenges in subjects who reported adverse reactions to MSG have included relatively few subjects and have failed to show significant reactions to MSG. Results of surveys and of clinical challenges with MSG in the general population reveal no evidence of untoward effects. We recently conducted a multicenter DBPC challenge study in 130 subjects (the largest to date) to analyze the response of subjects who report symptoms from ingesting MSG. The results suggest that large doses of MSG given without food may elicit more symptoms than a placebo in individuals who believe that they react adversely to MSG. However, the frequency of the responses was low and the responses reported were inconsistent and were not reproducible. The responses were not observed when MSG was given with food.

http://jn.nutrition.org/content/130/4/1058.full.pdf

Joe Perez 02-06-2014 08:43 PM


Originally Posted by Hinano (Post 1098978)
I don't need a study to tell me what MSG is doing to me.

And that's fine. If you have convinced yourself of this, then it's not my place to try and change your mind, nor would I want to attempt to do so.

I do question the validity of your test methodology, and would ask that you at least consider the notion that psychosomatic symptoms do in fact exist. For instance, here is an excerpt from an amateur experiment which attempts to follow proper scientific method, and produces interesting results:
... Renton also writes about experimenting on a friend of his named Nic, who claimed to have adverse reactions to MSG: Renton feeds him a meal full of the MSG and closely related naturally occurring glutamates that are found in a huge range of foods including tomatoes, cheese, Marmite, seaweed and Worcester sauce. But Nic feels no pain or adverse reaction after his glutamate-stuffed meal.

That's because he did not know he was eating MSG and other glutamates: like everyone else who complains of allergy or adverse reactions to MSG, Nic has psyched himself into believing that the benign substance makes him feel bad.
(...)
In China, where I live, you don't hear many complaints about MSG allergy. They're too busy gorging themselves on the stuff. Chinese people consume 1.6m to 1.8m tonnes of MSG crystals every year,
(...)
Nor do Italians complain about headaches after eating parmesan cheese (which tastes good because of the glutamates in it), Japanese don't worry about eating too much seaweed or dried shrimp (ditto), and even in Britain you don't often hear whining about adverse reactions to Marmite (ditto); you certainly don't get warnings from your doctor about the dangers of human breast milk to babies (ditto).
(...)
The persistence of the Chinese restaurant syndrome myth is a symptom of the hypochondria that has become fashionable in contemporary Anglo-American culture, and the failure of our educational systems to teach people the difference between quackery and hard science.


Full text: Why MSG allergy is fake science | Jeremy Goldkorn | Comment is free | theguardian.com


In other words, it is possible that you feel bad after consuming MSG because you have convinced yourself that you feel bad after consuming MSG.

Joe Perez 02-06-2014 08:54 PM

1 Attachment(s)

Originally Posted by Hinano (Post 1098978)
Also, I still recommend that you do a test yourself. Try buy some MSG and eat whatever amount you think is still safe and see what happens.

I consume significant quantities of MSG every time I go back to Florida to visit family during the holidays. My mother and sister both use quite a bit of the stuff in stews, soups, sauces, dips, etc. It's a staple seasoning at the casa de Perez. Comes in a little cardboard jar with a perforated cap that you can sprinkle it from. Looks like this:

https://www.miataturbo.net/attachmen...ine=1391738051

Hinano 02-07-2014 01:50 AM

Good discussion on MSG, thanks Joe for doing the homework. To clear a few things.

1. I had symptoms of headache, thirst, sweating and twitches before I knew ANYTHING about MSG. One day a friend was like this has MSG and told me about it.

2. How much MSG do you guys use? Because of the following,

3.

I checked your links and some links which they linked to. Let me quote two things "virtually all studies since then confirm that monosodium glutamate in normal concentrations has no effect on the overwhelming majority of people"

“Just like salt and sugar, it exists in nature, it tastes good at normal levels, but large amounts at high concentrations taste strange and aren’t that good for you,” Dr. Chaudhari said.

I don't really know all about MSG but I am willing to study more when I have a little bit more time BUT, from seeing what you linked too, it does not seem to take away from the chance that a portion of the population, could be sensitive to it, and or that portion size can make a big difference. Perhaps I was putting too much, and that that creates conditions of dehydration which leads to headaches and twitches? I am open to that idea. I guess I would like to then see if eating too much salt has the same effect. Maybe MSG has stronger dehydrating properties?? I have no idea and it sounds like it's worth researching...

But I got like a 100 pages to read for classes so this will have to be for another day.

Oh and just to add, I still sometimes have food with some MSG and I don't always have the symptoms and I think its because I eat very little BUT, my ass is healthy as hell and I NEVER, except when the sulfur in the air is especially bad from the volcano, have headaches. I know it's not hard science BUT, I know my body pretty well. I am truth and science oriented but regarding this, I must say, I trust my body to stay away from it and will let research catch up.

Keep us updated on your findings though, thanks Joe.

Edit: and thinking back at it though, I remember how much I was using. If I used the same amount of salt as I did MSG in my soups, I dont think I would get the headaches but it's worth trying out back to back.

Braineack 02-07-2014 08:35 AM

I get major heartburn when i drink maragaritas.

you should all avoid them.


this is only because I have a hiatal hernia, but so does everyone else in the world, right?

Joe Perez 02-07-2014 08:57 AM


Originally Posted by Hinano (Post 10998891)
I had symptoms of headache, thirst, sweating and twitches before I knew ANYTHING about MSG. One day a friend was like this has MSG and told me about it.

And that could well be. I'm certainly not a doctor or a biologist, nor do I know anything about you.

I'd caution merely against the pitfall of mistaking correlation for causality.

As an example, in 2011, Dr. Ka He of the University of North Carolina published a study in the American Journal of Clinical Nutrition, in which he studied 10,000 Chinese adults aged 18-65 over a period of several years, and concluded that there was a positive statistical correlation between the intake of high doses of MSG and weight gain. (full text)


The problem with that, and the thing which the popular press in the US and Europe failed to consider when republishing snippets of his findings, was that Dr. He never actually claimed that MSG causes weight gain, only that Chinese adults who consumed a large amount of it tended to gain weight. In fact, that very same study was later cited in a paper entitled "A lack of epidemiologic evidence to link consumption of monosodium L-glutamate and obesity in China."

Of course, that same segment of the population who tend to consume meals rich in MSG also tended to have a higher caloric intake overall, to lead a more sedentary lifestyle, to smoke, and in general to be less healthy overall. So why wouldn't they be expected to gain weight?

Joe Perez 02-07-2014 09:44 AM


Originally Posted by Hinano (Post 1099889)
I checked your links and some links which they linked to. Let me quote two things "virtually all studies since then confirm that monosodium glutamate in normal concentrations has no effect on the overwhelming majority of people"

Well, as I said earlier, this discussion, for me, breaks down into two main categories.

The first is chronic (long-term) effects, such as claims that MSG causes neurological harm by way of the ill-defined "excitotoxic damage." 100% of all available scholarly research conclusively and unambiguously disproves these claims.

The second is acute (short-term) effects, which may also be further subdivided into questions as to whether a certain percentage of the population are abnormally glutamate-sensitive.

The last of the four papers which I linked to previously, from Geha et al, entitled Review of Alleged Reaction to Monosodium Glutamate and Outcome of a Multicenter Double-Blind Placebo-Controlled Study does a really good job of approaching this question.

To summarize, the authors both reviewed existing literature and also conducted several original trials using proper control and blinding techniques, to look specifically for correlations between MSG consumption and the acute symptoms commonly described (headache, chest pain, flushing, etc) in those individuals who self-identify as being sensitive to MSG. I urge you to read the paper fully (it's not long, and is an easy read), but I'll point out a few highlights:


We recently conducted a multicenter DBPC (double-blind,
placebo-controlled) challenge study in 130 subjects to analyze
the response of subjects who report symptoms from ingesting
MSG. The results suggest that large doses of MSG given
without food may elicit more symptoms than a placebo in
individuals who believe that they react adversely to MSG.
However, the frequency of the responses was low and the
responses reported were inconsistent and were not reproducible.
The responses were not observed when MSG was given with food.
So that, right there is interesting. Even if the number of people who are sensitive to MSG is only as many as who are allergic to cats (about 8% of the population), that sample of 130 people should have captured 10-11 people with a bona-fide MSG sensitivity who produced consistent, repeatable responses. Instead they had none.


A drink vehicle with a novel taste that could
effectively mask the taste of MSG was used to challenge
individuals who believed themselves to be MSG sensitive.
Of
30 such individuals with whom contacts were made, only six
agreed to be tested. When these individuals were challenged
with 6 g of MSG in a double-blind, placebo-controlled manner,
it was found that four of the six did not react to either
substance, whereas two reacted to both MSG and placebo.
Of
the subjects who reacted, one reported tingling of hands and
warmth behind the ears after both MSG and placebo; the
other subject experienced tightness of the face after ingesting
either substance. The remaining four individuals who had
ascribed their previous symptoms such as headache, nausea,
tongue swelling and uncontrollable coughing to MSG ingestion,
did not react to either substance (Kenney 1986).
Here we have a very well carried-out test, which focuses specifically on individuals who already believe themselves to be adversely affected by MSG, using a blind trial comparing MSG to a placebo in a vehicle which, somewhat uniquely, denies the subject any ability to detect the difference in taste between the two (this is a key factor missing from most earlier studies.)

When these individuals were tested, none of them reported an adverse reaction to MSG while reporting no reaction to a placebo. Or put another way, they reported the same reaction to a placebo as they did to MSG.


Clinical studies with MSG ingested with food.
Studies in
which MSG was administered with food have shown an absence
of CRS symptoms. Oral administration of up to 147 g/d
of MSG to adult humans as the sole source of nonessential
nitrogen for 2–6 wk appeared to cause no clinical pathologic
changes, and no CRS symptoms were manifest
(Bazzano et al.
1970).
When 3 g MSG was
administered in 150 mL of beef bouillon at lunch time to 73
healthy subjects either in an open label or double-blind design
with each subject acting as his or her own control, no differences
in symptomatology were found between the control and
MSG-treated groups
(Morselli and Garattini 1970, Zanda et
al. 1973).
In a study to examine the absorption of glutamic
acid from solutions of MSG or a casein hydrolysate, 60 mg
MSG/kg casein hydrolysate or a mixture of the two were
administered to 12 healthy adults; no general ill effects were
observed (Marrs et al. 1978). In other studies, 60–150 mg
MSG/kg body weight was given to 14 adults and 13 infants
with a typical Chinese rice porridge meal. No adverse reactions
were observed
(Tung and Tung 1980).
Unlike the previous, which looked specifically at high-doses of MSG all by itself, the data above examine high doses of MSG in an otherwise normal meal, and reveal absolutely no adverse results whatsoever.





So is any of this absolutely conclusive? Well, it's darn close. If we accept this data as true, then it is possible (though not statistically probable), that a very small percentage of the population may react adversely to high doses of MSG taken all by itself without food. This same group, however, exhibits a strong tendency to report the same symptoms when they believe that they are consuming MSG but are instead given a placebo.

y8s 02-07-2014 10:45 AM


Originally Posted by Joe Perez (Post 1099835)
Huh? If you mean the one in post #167, I'm not sure I see the point. It doesn't really look much different from the one I use right now.


EDIT: I didn't mean for that to sound snide- if I'm missing something, please educate me.

No snideness assumed. I guess you have clarified for me that my amazon search skills were thwarted by amazon's terrible search capabilities.

I had intended to link to a scale that measures body fat percentage. like this one:


Truly a "butt dyno"

Braineack 02-10-2014 11:12 AM

2 Attachment(s)
Gotta love Wal-Mart:

Joe Perez 02-10-2014 08:18 PM

6 Attachment(s)

Originally Posted by Braineack (Post 1100665)
Gotta love Wal-Mart:

Wow. MSG *AND* grains in the same cart? Are you trying to kill yourself?


:giggle:



This is the conveyance of MSG which I am most familiar with:

https://www.miataturbo.net/attachmen...ine=1392081536

Goya Sazon is a staple seasoning in Latin-American cooking, and is found in every self-respecting kitchen in the Caribbean. Cuban women put this on everything- meat, seafood, frijoles negros, you name it.

Of course, it's only about 75% MSG, and it also contains a few other ingredients (garlic, cumin, saffron) which complement the cuisine of the islands rather well, but would tend to clash with the Cantonese palate. I managed to track down some Accent over the weekend while up in Catskill, and so I now have my very own bottle of pure, undiluted MSG as well:

https://www.miataturbo.net/attachmen...1&d=1392078918

(In retrospect, I would imagine that I probably could have just ridden down to Chinatown and gotten some there.)



I've also re-discovered the pleasure of cooking. Started emulating some of the dishes I've had from Precious in my own kitchen, such as tonight's entree of grilled chicken with string beans, in a pineapple-chili sauce (with lots of chili, a healthy dose of pure MSG, some powdered ginger and grated orange rind), with a side of short-grain brown rice.

https://www.miataturbo.net/attachmen...1&d=1392079521

Deeeee-lish.

y8s 02-11-2014 09:32 PM

1 Attachment(s)
While you jokers were out buying umami, this guy was whipping up this:

https://www.miataturbo.net/attachmen...ine=1392172355

ingredients: butter
recipe: bring to a boil over med-hi heat, on medium simmer 7-10 minutes until golden.

Now... amazon sells various types of MSG and I should probably get some.

Joe Perez 02-13-2014 10:18 PM

2 Attachment(s)
I'm starting to get good at these:

https://www.miataturbo.net/attachmen...ead-sesame-jpg

Chicken breast pan-seared until well-browned, with fresh string beans and frozen snow peas, some finely-chopped chilis, a dollop of storebought sesame-teryaki sauce, a healthy dose of Sriracha, some sliced pickled ginger, and of course, a decent sprinkling of pure MSG.

I do need to start using all fresh veggies- the frozen stuff just isn't cutting it anymore in terms of texture, and given that I have three hippie / organic grocers within a few blocks, there's just no excuse for not dropping by every other evening for a fresh take.

Joe Perez 02-13-2014 10:42 PM

2 Attachment(s)

Originally Posted by y8s (Post 1101350)
Now... amazon sells various types of MSG and I should probably get some.

It never would have occurred to me to look on Amazon, but you're quite right.

And in so searching, I've come to question the veracity of some of Amazon's claims:

https://www.miataturbo.net/attachmen...1&d=1392349330

y8s 02-14-2014 09:58 AM


Originally Posted by Joe Perez (Post 1102178)
It never would have occurred to me to look on Amazon, but you're quite right.

And in so searching, I've come to question the veracity of some of Amazon's claims:

https://www.miataturbo.net/attachmen...1&d=1392349330

Might be just the thing Hinano is looking for to squelch his reaction to MSG.

Joe Perez 02-14-2014 10:33 AM


Originally Posted by y8s (Post 1102238)
Might be just the thing Hinano is looking for to squelch his reaction to MSG.

Hahahaha. MSG-free MSG, for those with a high sensitivity to glutamate, and are therefore unable to consume ripe tomatoes, Parmesan cheese, scallops, mushrooms, corn, walnuts, broccoli, sweet potatoes, or human breast milk.


I'm kind of wondering where everyone has gone lately. This thread seems to be quieting down just at a time when it was becoming quite interesting...

JasonC SBB 02-14-2014 10:39 AM

Great, windows shut down to do an update without asking, just as I was finishing a long reply. Here's a shortened version.

Perhaps it's the combo of MSG and something else that causes symptoms in some individuals.

Re: starch intake - my original hypothesis may only be true for a subset of the population, and can change depending on gut flora. My own starch tolerance has greatly increased after regular raw potato powder (fermentable fiber) intake, which feeds the good bacteria, so much so that despite now having modest rice/potato intake, my 5-pack is starting to show up (4 dinner rolls and a meat loaf). My blood sugar numbers are better than ever (70-85 fasting and pre-meal, <120 post meal peak despite modest amounts of starch). Maybe Joe never had too much antibiotics and always had enough fermentable fiber to maintain his gut flora.

A fairly recent discovery has shown that the intestines and gut flora play a huge role in blood sugar regulation (and thus bodyfat regulation) and starch digestion.

Joe if you love brown rice, at least prepare it properly by soaking it to reduce the anti-nutrients:
Most Effective Way to Reduce Phytic Acid in Brown Rice | Kitchen Stewardship | A Baby Steps Approach to Balanced Nutrition

Braineack 02-14-2014 12:14 PM

1 Attachment(s)
I make healthy food:

This is ginger-soy salmon steamed over top of carrots, chives, and mushrooms with quinoa.

https://www.miataturbo.net/attachmen...ine=1392398087

I used kosher salt, no msg.

Joe Perez 02-14-2014 02:53 PM

2 Attachment(s)

Originally Posted by JasonC SBB (Post 1102249)
Perhaps it's the combo of MSG and something else that causes symptoms in some individuals.

Re: starch intake - my original hypothesis may only be true for a subset of the population, and can change depending on gut flora.

Without specifically passing judgement on what you've said here, I must admit that my intuitive reaction is "That's the wonderful thing about advice which is scientifically unsound and runs contrary to commonly-accepted doctrine. Every time one part of it gets disproven, it's easy to say 'well, perhaps this is true only under this one specific boundary condition, which was the one thing that your rigorous, academic test failed to explore.'"






Joe if you love brown rice, at least prepare it properly by soaking it to reduce the anti-nutrients:
Most Effective Way to Reduce Phytic Acid in Brown Rice | Kitchen Stewardship | A Baby Steps Approach to Balanced Nutrition
I will admit that I have had time only to perform a very cursory examination here, and I promise that I will do more research later on.

For the moment, my immediate takeaway is that it would seem that opinions concerning the "evilness" of phytic acid are not universally shared, even outside of the mainstream academic / medical community. For instance:

Phytic acid’s preventative properties:

CANCER

Foods higher in phytic acid seem to enhance the activity of natural killer cells and inhibit tumor growth.
Those who consume more phytic acid are less likely to succumb to breast and prostate cancer. Exposing the colon to less iron seems to decrease the risk of colon cancer.


CARDIOVASCULAR DISEASE

Phytic acid helps prevent hardening of the arteries and platelet formation.


KIDNEY STONES

With some phytate being excreted in the urine, this may improve kidney health and prevent stones.


INSULIN RESISTANCE

Phytic acid plays a role in pancreatic function and insulin secretion. And it may reduce the glycemic response from meals, meaning you feel full for longer.




In the balance

Is phytic acid worth worrying about? Maybe not, for most of us.

One study showed that subjects consuming a Mediterranean-style diet that included 1000-2000 mg of phytic acid per day did not suffer from reduced mineral bioavailability.

At the same time, certain people might have to be more wary.

In particular, iron intake and absorption can be critical for infants nearing six months of age. So when plants are added to infants’ diets, it may be important to adopt strategies to reduce phytic acid and enhance iron absorption.



Summary and recommendations

In healthy people eating balanced diets, phytic acid’s effects on iron, zinc, and manganese status is minimal and it doesn’t seem to cause nutrient deficiencies.

To argue that some plant foods are “unhealthy” because of their phytic acid content seems mistaken, especially when phytic acid’s potential negative effects on mineral assimilation may be offset by its health benefits.


Source: Precision Nutrition » All About Phytates (Phytic Acid)


I'll also note that the particular brown rice which I am using is pre-germinated, and that the label on the back contains a hilarious error which makes me question whether eating germinated brown rice might cause some kind of neurotoxic harm:

https://www.miataturbo.net/attachmen...1&d=1392407723

JasonC SBB 02-16-2014 04:39 PM

I didn't mention that the soaking reduces lectins.
What Are Lectins and Why Should We Care? | Norcal Strength & Conditioning
The Lowdown On Lectins | Mark's Daily Apple

Joe Perez 02-17-2014 09:19 AM


Originally Posted by JasonC SBB (Post 1102861)
I didn't mention that the soaking reduces lectins.

I'd say there are a lot of things you didn't mention. :D


But seriously, I'm just going to quote the first two sentences of the first link you posted there, so that everyone can soak them in (pun intended):
We all know that sugar is bad for us, that legumes should be avoided and it’s obvious that gluten is the devil. Right!?!?!
It's obvious that gluten is the devil.

Riiiiiiiiiiiiiiiiiiight. :giggle:




Anyway, moving on...

Weight seems to be holding for the moment right around 200-201, which is interesting. Based again on subjective analysis (eg: I didn't buy Y8s' fancy scale), I seem to be replacing fat with muscle, as I have hit the innermost notch on my belt and had to punch a new one, and my size 38 pants are now officially way too lose.

Makes me wonder if the low-carb / high-fat / no-grain diet was causing harm to my health and metabolism which went beyond simple weight gain...

y8s 02-17-2014 09:38 AM


Originally Posted by Joe Perez (Post 1103000)
I'd say there are a lot of things you didn't mention. :D


But seriously, I'm just going to quote the first two sentences of the first link you posted there, so that everyone can soak them in (pun intended):
We all know that sugar is bad for us, that legumes should be avoided and it’s obvious that gluten is the devil. Right!?!?!
It's obvious that gluten is the devil.

Riiiiiiiiiiiiiiiiiiight. :giggle:




Anyway, moving on...

Weight seems to be holding for the moment right around 200-201, which is interesting. Based again on subjective analysis (eg: I didn't buy Y8s' fancy scale), I seem to be replacing fat with muscle, as I have hit the innermost notch on my belt and had to punch a new one, and my size 38 pants are now officially way too lose.

Makes me wonder if the low-carb / high-fat / no-grain diet was causing harm to my health and metabolism which went beyond simple weight gain...

Unnaccounted for Joe lifestyle variables: new woman in your life. Raises physical activity and testosterone levels. Both of these can increase muscle and reduce body fat.

JasonC SBB 02-17-2014 12:54 PM

Here you go Joe, knock yourself out:
non-celiac - PubMed - NCBI
What is Gluten | Primal Body Primal Mind Diet and Nutrition

On the latter one, I acknowledge that gluten may have a dose-response curve wherein modest amounts may not do harm to non-sensitive individuals.

mgeoffriau 02-17-2014 07:03 PM

Get cold, get skinny.

Embrace the cold: Evidence that shivering and exercise may convert white fat to brown -- ScienceDaily

JasonC SBB 02-17-2014 09:40 PM

A bit of what Jack Kruse has been saying...

Joe Perez 02-18-2014 09:11 AM


Originally Posted by y8s (Post 1103005)
Unnaccounted for Joe lifestyle variables: new woman in your life. Raises physical activity and testosterone levels. Both of these can increase muscle and reduce body fat.

We will not be eliminating that variable from the test.



Also, my "do not feed the troll" sense is tingling, however I believe I owe Jason the courtesy of a response here:


Originally Posted by JasonC SBB (Post 1103052)

When you post things like this, I honestly can't decide whether you're being sarcastic, you're deliberately trolling me, or if you genuinely think that I am going to be able to glean useful information from a link to a list of titles of papers on PubMed.

Can you understand why I might feel that way, given the proper context?

JasonC SBB 02-18-2014 01:03 PM

You didn't like the 2 links I showed, so I gave you more, for you to browse.

Here's a fascinating interview of a guy who did a bunch of ground-breaking research.
Pioneering Researcher Alessio Fasano M.D. on Gluten, Autoimmunity & Leaky Gut

These quotes are damn interesting:


What is the difference between everybody and the people that develop a problem with gluten like celiac disease is that while for me, for example, because I don’t have a problem. I eat a Big Mac. I have gluten in there. These fragments release zonulin, which increases (intestinal) permeability. Stuff comes through, including gluten. My immune system that is tuned to do the job right will clean up the mess, and I will not even know that all that happened. Also because this open-and-close is short. It’s a matter of minutes that it will open and a matter of minutes that will turn to be closed. People with celiac disease, on the other hand, when they do something like that, not only do they have much more zonulin produced than I do, but also the opening is much more prolonged because these doors get stuck open, and therefore you give much more time for substances from the environment, including gluten, to come through. And now on this other side, you find this immune system that is not tuned to do the job right, and when they see this enemy, they start to mount an immune response to attack your own body, and that leads to celiac disease."
My question is, is there harm in "normal" people when ingesting gluten which is known to make the intestines temporarily permeable?


The differences between Celiac Disease and gluten intolerance
Chris Kresser: OK, well, that’s very clear. Dr. Fasano, we’ve been talking so far about celiac disease, but we haven’t yet touched on the phenomenon known as gluten intolerance. Can you talk a little bit about the difference between the two ... ?

Dr. Alessio Fasano: Until the recent past, we were convinced that the only reaction that we have to gluten would be celiac disease, so this autoimmune reaction to gluten. Over the years, with the increase of awareness about celiac, with the increase of products in the market and with the popularity of what this gluten-free diet was all about, more and more people became aware of celiac disease and the gluten-free diet. ...

.. they were desperate because nothing else explained their symptoms, they decide, despite the negative results, to try the diet no matter what. And some of them, sure enough, had their symptoms improved or completely resolved.

So as typically happens in these situations, it was from the grassroots that the problem really became a problem, because when we saw this critical mass of people come into our clinic, at the beginning we sent them away. We said, you know, you don’t have celiac disease. You have no reason to be on a gluten-free diet. But when we saw this phenomenon to take great proportion, we asked ourselves: Is that possible that all these people are nuts? Are they all responding as a placebo effect? So we started to dig into this situation a little bit more, and sure enough, we discovered that there is another form of gluten reaction that we don’t call gluten intolerance anymore because we went through a revision of nomenclature, but we call it gluten sensitivity. And it turns out to be an immune response to gluten not on an autoimmune basis like in celiac disease, not even on an allergic basis because we know that sometimes wheat can induce an allergic reaction like any other foodstuff.
.. it’s a different form of immune reaction that will create a minimal inflammation without damage of the intestine. And that caused the symptoms intestinally and extraintestinal that these people may eventually experience when ingesting gluten.

...We were shocked — shocked — to learn that celiac disease doubled every 15 years in this court. It was 1 in 500 in the ‘70s, 1 in 250 in the mid-’80s, and 1% in 2000.... there was something else that was going on here. We had two ladies that for 70 years-plus eating gluten had no problem whatsoever. They were tolerating gluten. No problem with ingesting gluten. Then all of a sudden, they lost this luxury and they switched from tolerance to immune response and developed autoimmunity in their late 70s. This implies two questions that really, I believe, is the most intriguing part of this entire story for the years to come: Number one, what kind of tricks did these ladies use to tolerate what is an indisputable trigger of autoimmunity for people genetically predisposed to celiac disease? We learned that we may have the holy grail to prevent autoimmunity in general. It is material for a Nobel prize. Number two, more feasible, is to answer the question, what happened to these ladies that after so many years lost that luxury and then switched from tolerance to an immune response? And here, I believe that the most likely answer is the microbiome, the bacteria that live with us in symbiosis, have to be the ones that made them to switch from tolerance to immune response.
Resistant starch such as raw potato powder has been shown to improve the gut flora. Might it prevent or reverse autoimmune diseases and/or improve gluten sensitivity?

mgeoffriau 02-18-2014 07:33 PM

Man, watching Joe double-down on his stupid position is funny.

mgeoffriau 02-18-2014 07:36 PM

Of course, if I had a magic metabolism that responded to cutting grains, sugars, and carbs by gaining weight, I might find modern dietary and nutritional research baffling too.

mgeoffriau 02-18-2014 07:48 PM

Oh I almost forgot this. I ate Joe Perez's normal diet for one week and gained 100 lbs of fat.

Joe Perez 02-19-2014 08:52 AM

2 Attachment(s)
Sidebar: whoever edited the thread title, well-played. :bigtu:



Originally Posted by JasonC SBB (Post 1103464)
You didn't like the 2 links I showed, so I gave you more, for you to browse.

That's true, and it merits a better explanation.


The first of the links you gave in post #282 is merely a list of papers available through PubMed which match the search phrase "non-celiac." None of those which I have clicked on thus-far return a full-text result, and only a few have comprehensive abstracts. So this is essentially a content-free link inasmuch as I can tell. By contrast, I have endeavored only to cite sources which are actually readable by all, so, quite frankly, I find this sort of thing to be rather lazy, and somewhat offensive.

A bit of light searching on slightly different keywords turns a number of articles written by credible authors who aren't trying to sell me anything, which strongly indicate that blanket statements such as those which have been made previously are far from "obviously true." Arguments which run contrary to established principles and which rely mostly upon subjective testing and conjecture (rather than controlled scientific testing) bear a special burden of proof, which is thus far unmet in this context.

The tone thus far in this particular line of conversation reminds me somewhat of a debate over religion, conducted with a person who bears a strong religious conviction. Such a discussion might fairly be summarized as:
1: This is obviously true because the Bible says so.
2: Huh? You can't use an alleged source as proof of itself. That's like me saying "I am God, because I say I am."
1: Stop being a closed-minded bigot! You're attacking me for no reason!
2: ?!?

I'm really trying quite hard to keep an open mind and subject all opinions and assertions to the same rational scrutiny. It bothers me somewhat to be accused of being [a contrarian / deliberately obtuse / willfully ignorant] for this. I'm not specifically saying that you have done this (though certain people have), only pointing out that it's a vibe I'm picking up.





The second link deserves special attention, as it is particularly insulting. Twice in this thread I have established a specific point wherein the trustworthiness / legitimacy of sources is concerned:

The first was in post #68 back in Oct of last year, when I stated "In other words, it doesn't matter how old the research is, if the only "facts" which contradict it are actually based on speculation, hysteria, slick marketing and misrepresentation of data for the purpose of selling self-help books and lifestyle coaching."

The second was in post #261 just a week or two ago, to wit "Among "trustworthy" sources (eg: those involving proper control / blinding techniques, those published in peer-reviewed journals or as academic theses, and not coming from laypersons who have an obvious financial motivation such as the sale of books, herbal remedies, etc)..."

So, I hope you can understand why I find it especially hilarious to see you send me a link to the following:

https://www.miataturbo.net/attachmen...ine=1392817929


In general, I make it a point to place special scrutiny on advice given to me by individuals who are actively trying to sell me something.

Joe Perez 02-19-2014 09:09 AM


Originally Posted by mgeoffriau (Post 1103607)
Of course, if I had a magic metabolism that responded to cutting grains, sugars, and carbs by gaining weight, I might find modern dietary and nutritional research baffling too.

While I understand that this is intended as sarcasm, I'm struggling to understand the point of it.

During the period of Nov-Dec 2013, I embarked upon a high-calorie diet which happened to be low in carbohydrates and high in fat and protein. During that time, I gained weight (and fat.) This is hardly surprising- to the contrary, I'd have considered it to be "magic" if I had lost weight (and fat) during this time, as that would have been evidence of my body expressing a discriminatory metabolism (eg: preferring one source of caloric intake vs. another), which would have been contrary to most of what is understood in the scientific and academic communities to be factual in this regard.

During the period of Jan-Feb 2014, I have embarked upon a lower-calorie diet, which happens to displace calorie-dense foods which are high in fat (cheeses, fatty meats, etc) with less-calorie-dense foods which happen to be high in carbohydrate content (vegetables, grains, rice, etc.) During this time I have lost weight and fat. This, again, is consistent with a rational expectation based upon known principles of human nutrition.


If you feel that I continue to be in error in either my methodology or the interpretation of the resultant data then do please pay me the courtesy of a more specific interposition. Your insults, while moderately amusing and so far tastefully relevant, are not productive insofar as arriving at a more comprehensive understanding of the facts in this matter.








Originally Posted by mgeoffriau (Post 1103611)
Oh I almost forgot this. I ate Joe Perez's normal diet for one week and gained 100 lbs of fat.

This seems improbable. 100 lbs in one week rather stretches the bounds of what one would expect to be physiologically possible. I assume therefore that it is also sarcasm, but whether you genuinely intended it to somehow make a positive contribution to the thread (and are therefore an idiot) or you just enjoy making snide comments for the purpose of derailing conversations (and are therefore an ass) is something to which I won't hazard a guess.




That said, I did order the specific analytical scale that Y8s linked to, as I find this phenomenon to be most interesting and wish to have a clearer perspective into it. I wish that I'd had it for the past two months in order that I'd have some "before" data, but I shall have to resign myself to a forward-looking perspective. As it stands now, I've no desire to return to the state that I was in around the first of the year.

mgeoffriau 02-19-2014 09:34 AM

Ah, now Joe's all mad that someone's derailing the thread in which he set out to demonstrate that adding several hundred calories per day of any food will result in weight gain and thereby disprove...something.

y8s 02-19-2014 09:54 AM


Originally Posted by Joe Perez (Post 1103753)
That said, I did order the specific analytical scale that Y8s linked to, as I find this phenomenon to be most interesting and wish to have a clearer perspective into it. I wish that I'd had it for the past two months in order that I'd have some "before" data, but I shall have to resign myself to a forward-looking perspective. As it stands now, I've no desire to return to the state that I was in around the first of the year.

I know you're trying to thwart the "common wisdom" in this thread but please make sure you take your body fat readings at approximately the same time each day under similar conditions. In other words before your dump and shower, after you chug your morning water, but before your breakfast. Or whatever place it fits into your routine. You may want to consider multiple readings during the day to get a feel for your true BF%.


Originally Posted by Wikipedia
Many of the early research studies showed that BIA was quite variable and it was not regarded by many as providing an accurate measure of body composition. In recent years technological improvements have made BIA a more reliable and therefore more acceptable way of measuring body composition. Nevertheless it is not a "gold standard" or reference method. Like all assessment tools, the result is only as good as the test done. Although the instruments are straightforward to use, careful attention to the method of use (as described by the manufacturer) should be given.

Simple devices to estimate body fat, often using BIA, are available to consumers as body fat meters. These instruments are generally regarded as being less accurate than those used clinically or in nutritional and medical practice. They tend to under-read body fat percentage.[2]

Dehydration is a recognized factor affecting BIA measurements as it causes an increase in the body's electrical resistance, so has been measured to cause a 5 kg underestimation of fat-free mass i.e. an overestimation of body fat.[3]

Body fat measurements are lower when measurements are taken shortly after consumption of a meal, causing a variation between highest and lowest readings of body fat percentage taken throughout the day of up to 9.9%.[4]

Moderate exercise before BIA measurements lead to an overestimation of fat-free mass and an underestimation of body fat percentage due to reduced impedance.[5] For example moderate intensity exercise for 90–120 minutes before BIA measurements causes nearly a 12 kg overestimation of fat-free mass, i.e. body fat is significantly underestimated.[6] Therefore it's recommended not to perform BIA for several hours after moderate or high intensity exercise.[7]

BIA is considered reasonably accurate for measuring groups, or for tracking body composition in an individual over a period of time, but is not considered sufficiently accurate for recording of single measurements of individuals.[8]

The accuracy of consumer grade devices for measuring BIA has not been found to be sufficiently accurate for single measurement use and are better suited for use to measure changes in body composition over time for individuals.[9]

(source Bioelectrical impedance analysis - Wikipedia, the free encyclopedia )


Joe Perez 02-19-2014 10:00 AM


Originally Posted by y8s (Post 1103769)
I know you're trying to thwart the "common wisdom" in this thread but please make sure you take your body fat readings at approximately the same time each day under similar conditions. In other words before your dump and shower, after you chug your morning water, but before your breakfast.

Yes, I've observed similar fluctuations in weight measurements taken throughout the day as well.

I always take "official" weight measurements first thing in the morning, after my usual bowel movement but before having consumed any food or drink.

This routine will not change simply due to the purchase of a different scale.


From the Wiki article you linked to: "The accuracy of consumer grade devices for measuring BIA has not been found to be sufficiently accurate for single measurement use and are better suited for use to measure changes in body composition over time for individuals." I would consider this to be true of pretty much all consumer-grade measuring equipment, and treat this no differently than I would the oil pressure gauge on my engine. Does 45PSI actually mean 45 PSI? Doesn't matter, so long as it's consistent. I'm looking for trends here, which is why I added to my above "I wish that I'd had it for the past two months in order that I'd have some "before" data..."

JasonC SBB 02-19-2014 10:59 AM

Joe, Nora Gedgaudas (author of book) was practicing what she preached before she started writing her book. There are many people who have a talent, discover a niche, and decide that writing a book / selling services, is a win-win for them and their customers. Andrew was giving out free advice on radiators and brakes before he decided to start Trackspeed. Because he now makes money on radiators and brakes, does that make his advice suspect?

The pubmed link was to a bunch of articles to non-celiac gluten sensitivity. The link you made fun of has a simple diagram with the action of gluten. That, and the later quotes, is to try to show you that the gluten stuff is far, far from imagined. The question in my mind remaining is, (and which is asked in the interview link) how damaging is it to non-sensitive individuals, or, can the latter develop sensitivity over time with large intakes of it?

Something I haven't mentioned in this thread is that someone close to me tested positive for AutoImmune thyroid antibodies, after I insisted to their doctor to do the detailed test (he'd initially refused). This person is in the early stages of Hashimoto's hypothyroidism. This is a disease where the immune system destroys the thyroid gland until thyroid output drops and misery sets in. The vast majority of Hashimoto's is caused by a reaction to GLUTEN. Several percent of the population is in some stage of Hashimoto's.

This person had NO PREVIOUS SYMPTOMS of gluten sensitivity, but had an anomalous simple thyroid test result years ago which they'd chalked up to a testing fluke. Turns out that in the early stages one symptom is fluctuating thyroid output. The previous doc didn't suspect anything from the anomalous test result.

So here is an example of someone whose immune system was on the road to being destroyed by gluten exposure with *no* symptoms. The interviewee whose quote I pasted discusses 70 year olds who suddenly developed a severe gluten sensitivity. Would they have been fine had they consumed half as much wheat all their life? Dunno.

And here is a study that shows that modern wheat causes more symptoms than ancient varieties of wheat. Presumably because it has more gluten, because it makes bread stickier nicer and chewier, and thus is bred in over generations:

New Study Vindicates William Davis: Modern Wheat is more Toxic than Ancient Varieties | Rosemary Cottage Clinic

In the interview I linked, they'd observed that gluten sensitivity has been rising dramatically in the last decades. Increased gluten in GMO wheat? Widespread antibiotic use?

Do I think it's prudent to reduce wheat/gluten intake for the non-symptomatic population given all this? Yes. Wheat is a low-nutrient-density food anyway. And lectins in general too. You can get way more nutrients for the same calories eating sweet potatoes and veggies anyway.

Remember this starting premise: foods especially plant foods which were introduced to the human genome only in the last 10,000 years are suspect because any genetic adaptations to said foods are typically "shallow", and are not widespread in the population (thus the individuality). The well-known exceptions are starchy tubers, vegetables (assuming no sensitivity to things like oxalates and nightshades), and fruit (though note that modern fruit breeds have way more sugar than those pre-neolithic times, and high fructose consumption is implicated in high blood pressure, obesity, gout, and non-alcoholic fatty liver disease).

I'm hoping that outfits like http://www.23andMe.com will come up with testing for genes that tell you how sensitive you are to things like lactose, gluten, soy, casein, albumen, nightshades, oxalates, starch, FODMAPs, etc.

Lastly, on the "allergic to cats" analogy - bear in mind there's a difference between food allergy, sensitivity, and intolerance. Food sensitivity is the most pernicious because it's an immune system reaction which may not be immediately obvious and can be very damaging. It's also the most difficult to do a lab test for.

Joe Perez 02-19-2014 11:23 AM


Originally Posted by JasonC SBB (Post 1103801)
The question in my mind remaining is, (and which is asked in the interview link) how damaging is it to non-sensitive individuals, or, can the latter develop sensitivity with large intakes of it?

I believe that I understand your thinking in the matter. I do, however, take issue with the presupposition which is implied in the question "...how damaging is it to non-sensitive individuals" Phrasing the question thusly is not entirely unlike asking someone "So, have you stopped beating your wife?" In neither case has the underlying question of fact been addressed. (Is gluten even harmful at all in normal individuals? Did Bob ever beat his wife in the first place?)


To elaborate a tad on why I might seem, to some, obstinately unwilling to blindly accept what is being said vis-à-vis the universal evils of gluten, a few counterpoints:



Dr. Daniel A. Leffler, director of clinical research at the Celiac Center at Beth Israel Deaconess Medical Center in Boston, doesn’t quite see the point of all the hype:
“Based on little or no evidence other than testimonials in the media, people have been switching to gluten-free diets to lose weight, boost energy, treat autism, or generally feel healthier. People who are sensitive to gluten may feel better, but a larger portion will derive no significant benefit from the practice.”
(source)



Likewise, Drs. Antonio Di Sabatino, MD, and Gino Roberto Corazza, MD, of Italy’s University of Pavia, explore the topic in their paper Nonceliac Gluten Sensitivity: Sense or Sensibility? published in the Annals of Internal Medicine (21 Feb 2012.) They note that:
“Claims [about gluten-free diets] seem to increase daily, with no adequate scientific support to back them up. This clamor has increased and moved from the Internet to the popular press, where gluten has become the new diet villain.
(…)
We must prevent a possible health problem from becoming a social health problem. Self-prescription of gluten withdrawal by a growing number of patients inevitably leads to a series of problems: subsequent inability to correctly diagnose or exclude celiac disease, deleterious health effects from the probably suboptimal adherence to a gluten-free diet in the case of patients with undiscovered celiac disease, and the high economic burden related to an unjustified gluten-free diet.”
Their findings also draw an interesting (though unspoken) parallel to our earlier conversation about MSG sensitivity, noting that some people may experience these symptoms when they eat foods containing gluten simply because they believe these foods will make them sick. Drs. Sabatino and Corazza conclude that common sense must prevail to prevent a gluten preoccupation from evolving into the conviction that gluten is toxic for most of the population.
(source)




Stefano Guandalini, MD, who is president of the North American Society for the Study of Celiac Disease, says:
“Someone who needs to be on a gluten-free diet and is closely monitored can benefit tremendously from it. But for everyone else, embracing this diet makes no sense.
(source)






These aren't liberal-arts majors conducting poorly-controlled, unblinded experiments at home, nor people who are pawns of any agro-industrial establishment or who are unfamiliar with gluten-sensitivity. These are doctors who research and specialize in the management of Celiac disease, and are uniquely qualified above all others to speak to the applicability of a gluten-free diet in humans.





But it gets weirder:

Further reading reveals that not only may a gluten-free-diet (GFT) provide no substantive benefit in the vast majority of healthy individuals, but that it does, in fact, have deleterious side-effects. Some are relatively minor, as noted by David A. Nelsen Jr., MD, MS in his peer-reviewed journal article Gluten Sensitivity: Fad and Fact.:
Is the GFD more or less healthy than a “regular” diet? Of course, this depends on the viewpoint that one takes. Gluten-free flours such as rice flour and cornstarch typically have a higher glycemic index compared to wheat-based flours. This may exacerbate insulin resistance, weight gain, and glucose intolerance.
(source)





Then you get into the really serious stuff, such as the study performed by Dra. Yolanda Sanz et. al. of the Spanish National Research Council, which she details in the rather verbosely titled Effects of a gluten-free diet on gut microbiota and immune function in healthy adult humans, published in the journal Gut Microbes:
Diet is a major environmental factor influencing gut microbiota diversity and functionality, which might be relevant to subjects following dietary therapies. Celiac disease (CD) is an enteropathy caused by an aberrant immune response to cereal gluten proteins and the only therapy is the adherence to a gluten-free diet (GFD). In this context, a preliminary study was conducted to establish whether the GFD in itself could modify the composition and immune properties of the gut microbiota.
(…)
This study included 10 healthy subjects, who were following a GFD over one month by replacing the gluten-containing foods they usually ate with certified gluten-free foods (with no more than 20 parts per million of gluten). Analyses of fecal microbiota and dietary intakes, indicated that populations of generally regarded healthy bacteria decreased (Bifidobacterium, B. longum and Lactobacillus), while populations of potentially unhealthy bacteria increased parallel to reductions in the intake of polysaccharides (from 117 g to 63 g on average) after following the GFD. In particular, increases were detected in numbers of E. coli and total Enterobacteriaceae, which may include opportunistic pathogens. This evidence suggests a disruption of the delicate balance between the host and its intestinal microbiota (dysbiosis), which might favor the overgrowth of opportunistic pathogens and weaken the host defences against infection and chronic inflammation via possible alterations in mucosal immunity.
(source)


So not only does going gluten-free NOT solve any problems in healthy individuals, it also alters your gut flora and allows harmful bacteria to grow in your gut.

I’m honestly a tad surprised that your research has not turned up any of the above, especially the last article detailing the disruption caused by a gluten-free-diet to beneficial gut microbes, in light of you recent emphasis on same, such as this entire thread, which is all about the care and feeding of gut microbiome.


The key point which I’m trying to make from all this is that very few absolutes exist in life, and dietary science is no exception. What is harmful to a small minority of individuals may be beneficial to the majority (eg: cat ownership is clinically proven to lower triglycerides and cholesterol, and decrease the risk of cardiovascular disease, stroke and heart attack. Sadly, cat ownership can also cause death by anaphylaxis, but ONLY in people who exhibit an abnormal immune response to certain proteins found in cat saliva.)


When we hear broad, sweeping statements such as “This food is evil and must absolutely be avoided,” this ought to be cause for considerable skepticism on the part of the informed reader.

mgeoffriau 02-19-2014 11:27 AM

Gluten increases intestinal permeability for everyone.

Gliadin, zonulin and gut permeability:... [Scand J Gastroenterol. 2006] - PubMed - NCBI

JasonC SBB 02-19-2014 11:43 AM

I apologize for my seeming "ninja edit", I mistakenly hit "post" instead of "preview". See again my post #295. I believe the balance of the evidence makes it prudent for everyone to eat low-gluten. Also note the distinction between Celiac disease, non-celiac gluten sensitivity, and non-sensitive individuals. I will argue that a proportion of the latter may have no outward sensitivity symptoms but are developing auto-immune disease (which has now grown to be the #3 killer in this country).

JasonC SBB 02-19-2014 11:46 AM

As for a gluten free diet negatively altering gut flora and increasing insulin resistance:

This may be true for some who remove gluten sources while increasing other starchy foods (e.g. "gluten free bread") instead of replacing them with veggies. It is stupid to make the first claim in the general case without clarification.

And now we have a lot of evidence that a stupid easy and cheap source of Resistant Starch (raw potato powder), improves gut flora:
http://freetheanimal.com/2013/11/res...omparison.html

mgeoffriau 02-19-2014 01:10 PM

Worth perusing.

Carb-Restricted diets - Ancestral Weight Loss Registry


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