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SARS-CoV-2 variants of concern and variants under investigation in England - Public Health England
In the first group of vaccinated people there were a total of 402 deaths, and in the second much larger group of unvaccinated people there were 253 deaths.
That gives a death rate of .86 percent among the vaccinated and .17 percent among the unvaccinated.
So yes, you've been right all along, the vaccine will reduce the number of hospitalizations -- but it increases your chances of death sustainably. But I mean, a brain clot sounds fun to me to combat a perfectly survival virus...
In-vitro studies conducted to date show that the clinical candidate PF-07321332 is a potent protease inhibitor with potent anti-viral activity against SARS-CoV-2
This is the first orally administered coronavirus-specific investigational protease inhibitor to be evaluated in clinical studies, and follows Pfizer’s intravenously administered investigational protease inhibitor, which is currently being evaluated in a Phase 1b multi-dose study in hospitalized clinical trial participants with COVID-19
NEW YORK--(BUSINESS WIRE)-- Pfizer Inc. (NYSE: PFE) announced today that it is progressing to multiple ascending doses after completing the dosing of single ascending doses in a Phase 1 study in healthy adults to evaluate the safety and tolerability of an investigational, novel oral antiviral therapeutic for SARS-CoV-2, the virus that causes COVID-19. This Phase 1 trial is being conducted in the United States. The oral antiviral clinical candidate PF-07321332, a SARS-CoV2-3CL protease inhibitor, has demonstrated potent in vitro anti-viral activity against SARS-CoV-2, as well as activity against other coronaviruses, suggesting potential for use in the treatment of COVID-19 as well as potential use to address future coronavirus threats.
“Tackling the COVID-19 pandemic requires both prevention via vaccine and targeted treatment for those who contract the virus. Given the way that SARS-CoV-2 is mutating and the continued global impact of COVID-19, it appears likely that it will be critical to have access to therapeutic options both now and beyond the pandemic,” said Mikael Dolsten, MD, PhD., Chief Scientific Officer and President, Worldwide Research, Development and Medical of Pfizer. “We have designed PF-07321332 as a potential oral therapy that could be prescribed at the first sign of infection, without requiring that patients are hospitalized or in critical care. At the same time, Pfizer’s intravenous antiviral candidate is a potential novel treatment option for hospitalized patients. Together, the two have the potential to create an end to end treatment paradigm that complements vaccination in cases where disease still occurs.”
Exploring the binding efficacy of ivermectin against the key proteins of SARS-CoV-2 pathogenesis: an in silico approach
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Results: Ivermectin was found as a blocker of viral replicase, protease and human TMPRSS2, which could be the biophysical basis behind its antiviral efficiency. The antiviral action and ADMET profile of ivermectin was on par with the currently used anticorona drugs such as hydroxychloroquine and remdesivir. Conclusion: Our study enlightens the candidature of ivermectin as an effective drug for treating COVID-19.
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It's almost like pfizer knows the vaccine is **** and the real treatment needs to be patient protected and sold for 50000x the cost...
but a bald 36yo reporter told me it's for horses, so I should probably shove a tube down my throat and wonder why i'm still not getting oxygen when my hemoglobins have been ripped apart from the virus...
Israel currently has the highest covid infection rate in the world. They also have one of the highest vaccination rates in the world. and have had mask policies in place for nearly the entire pandemic. they also implemented vaccine passports.
No point to those statements, just here waiting for the goalposts to move.
a registered democrat, and "accidental tourist," who "is not a trump supporter," in the "spur of the moment," put on a MAGA hat, took to the streets on Jan 6, "battled the police," and got arrested. Now he is pleading for a light sentence because he "is not politically active, is not and has never been a member of any right-wing or anti-government or extremist group and has, unfortunately, been publicly grouped with many others (whose) views he abhors".
Israel currently has the highest covid infection rate in the world. They also have one of the highest vaccination rates in the world. and have had mask policies in place for nearly the entire pandemic. they also implemented vaccine passports.
No point to those statements, just here waiting for the goalposts to move.
At this time last year, no one was vaccinated yet hospitalizations were less than half of what they are right now when over 70% of the population is vaccinated. (~99,000 vs ~30,000) [and it's not even a general election year]
Denver to close park plagued with crime, drug use and feces
Denver will temporarily shut down a park that has devolved into a haven for drug users, crime and human waste.
Civic Center Park and the adjacent areas will close beginning next Wednesday “until further notice” as the city cleans up and restores the green space.
“The current challenges within Civic Center Park have reached a tipping point, creating conditions that put the public’s health and safety at risk,” Mayor Michael Hancock said in a statement.
“This is the people’s park and we are taking steps so that everyone can once again feel safe and welcomed there,” the mayor said.
Officials said over the past “several months” conditions at the park have deteriorated.
Human and pet waste, an excess amount of rodent-attracting trash and needles and other drug paraphernalia have been spotted at the park in recent weeks.
Additionally, “the park and surrounding areas have become a hotspot for violence, crime, drug sales and substance misuse, jeopardizing the public’s ability to safely enjoy one of Denver’s treasured outdoor spaces,” the city said in a press release announcing the closure.
During the closure, the city will restore the park’s turf, address the rodent infestation, trim trees, install more lighting and reseed, among other upgrades.
“The goal of Denver Parks and Recreation is to restore Civic Center Park, Denver’s beloved National Historic Landmark in the heart of our city, by providing a safe, clean and inviting public space,” said Happy Haynes, Executive Director of Parks and Recreation.
Lockdowns, police state, forced quarantines/distancing, masks, vaccines, and taxes really work, people!!! Especially on isolated islands with strict travel restrictions and low population levels.
09-07-2021, 09:37 AM
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