The Current Events, News, and Politics Thread
Boost Pope
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Everything about that speech last night was just bizarre.
Like, if we weren't receiving a direct feed of it straight from the DC bureau, I'd have thought maybe it was a very clever deepfake by The Babylon Bee or something.
I mean, did anyone here watch Season 2 of Picard?
Anyway, in post-Soviet Russia:
Like, if we weren't receiving a direct feed of it straight from the DC bureau, I'd have thought maybe it was a very clever deepfake by The Babylon Bee or something.
I mean, did anyone here watch Season 2 of Picard?
Anyway, in post-Soviet Russia:
Boost Czar
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SCIENCEEEEEEEEEEEEEE EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE
https://igorchudov.substack.com/p/ba...trial-actually
https://igorchudov.substack.com/p/ba...trial-actually
So, the FDA just approved the new Ba.5 bivalent booster, based on a trial of exactly 8 mice.
Steve Kirsch, in a reply to my previous post about the Ba.5 booster being medical quackery, asked a question, what happened to the 8 mice in the trial? Did they die?
Given how amazing Steve is, I decided to take a look. Good thing I did!
The scientists extracted their blood for analysis.
Literally, the only data about these 8 mice come from the last two pages of Pfizer’s presentation. Pfizer analyzed their blood for antibodies:
Since this picture might seem indecipherable, let me first explain what it means. This picture shows the outcomes of three different concoctions:
Each bar shows the ability of the given vaccine to produce “neutralizing antibodies”. For every vaccine, there are five bars showing titers of antibodies, affecting the neutralization of each variant: neutralization of the original Wuhan virus, Ba1, Ba2, Ba2.12.1, and Ba4/5 by that specific vaccine.
The higher the values in the bar, the better, according to the FDA, although in real life these antibodies are more like electrolytes in Idiocracy: they are only good for counting and do not stop infections.
So, look at that red-circled set of bivalent booster bars. You will see something strange: the Ba.5 bivalent booster was incredibly consistent producing antibodies against the Wuhan variant. (look at the CONSISTENT tag and the arrows). The consistency is perfectly exemplary. Each mouse got an almost identical amount of Wuhan-related antibodies. Good!
However, the bivalent booster was extremely INCONSISTENT when producing antibody responses against Ba.5 variant. Look at the rightmost bar. I created a custom picture placing that bar right next to the logarithmic scale so you can see the problem:
You can see that the antibody titers for the Ba.5 booster, against Ba.5 variant, are all over the place! One mouse had a titer of 300, two more had titers of 700, two more had a titer of 1,500, one had a titer of 3,000, one had a titer of 7,000, and the last one had a titer of 22,000!
So, the 8 Pfizer standardized Balb/c mice, quite identical and reacting identically at producing Wuhan antibodies, reacted WILDLY DIFFERENTLY when producing Ba5 antibodies!!! One of them had an immune reaction producing 300 antibody titers, while another similar mouse produced 73 times more antibodies, or 22,000 titers!
Did the mouse who got a 73 times greater immune reaction, feel sicker? Did the mouse who got a 73 times lower reaction, get no protection from Ba.5 variant? Pfizer is not sharing that.
So, Zack would have 73 times more intense, severe, or however you want to call it, reaction compared to Adam!
Would Zack, with his 73 times greater reaction to the same concoction, be much more likely to die of myocarditis? Would Adam remain completely unprotected due to his 73 times lower reaction?
We have no idea!
Nobody has any idea about it: me, you, Pfizer, or the FDA.
But we are giving 171,000,000 doses of this inconsistent concoction to the American people based on this single-page 8-mouse data that nobody even bothered to look at closely.
Of the 171,000,000 future doses distributed, roughly 1/8 of them, or the highest-reacting 21,375,000 people, would have 73 times more severe and intense immune reaction than the bottom, lowest-reacting 21,375,000 people.
Steve Kirsch, in a reply to my previous post about the Ba.5 booster being medical quackery, asked a question, what happened to the 8 mice in the trial? Did they die?
Given how amazing Steve is, I decided to take a look. Good thing I did!
The scientists extracted their blood for analysis.
Literally, the only data about these 8 mice come from the last two pages of Pfizer’s presentation. Pfizer analyzed their blood for antibodies:
Since this picture might seem indecipherable, let me first explain what it means. This picture shows the outcomes of three different concoctions:
- BNT162b2 — the original 2020 Covid Vaxx — the first set of blue bars on the left
- OMI BA 4/5 — Vaccine based only on Ba4/5 variant spikes only — the second set of red bars in the middle
- BNT162b2 + OMI BA 4/5 — the so-called “Bivalent booster”, or a mix of Wuhan and Ba5 spike mRNAs that the Federal government plans on giving everyone in September. This is the circled set of purple bars on the right side of the picture. This last set is what we are interested in.
Each bar shows the ability of the given vaccine to produce “neutralizing antibodies”. For every vaccine, there are five bars showing titers of antibodies, affecting the neutralization of each variant: neutralization of the original Wuhan virus, Ba1, Ba2, Ba2.12.1, and Ba4/5 by that specific vaccine.
The higher the values in the bar, the better, according to the FDA, although in real life these antibodies are more like electrolytes in Idiocracy: they are only good for counting and do not stop infections.
So, look at that red-circled set of bivalent booster bars. You will see something strange: the Ba.5 bivalent booster was incredibly consistent producing antibodies against the Wuhan variant. (look at the CONSISTENT tag and the arrows). The consistency is perfectly exemplary. Each mouse got an almost identical amount of Wuhan-related antibodies. Good!
However, the bivalent booster was extremely INCONSISTENT when producing antibody responses against Ba.5 variant. Look at the rightmost bar. I created a custom picture placing that bar right next to the logarithmic scale so you can see the problem:
You can see that the antibody titers for the Ba.5 booster, against Ba.5 variant, are all over the place! One mouse had a titer of 300, two more had titers of 700, two more had a titer of 1,500, one had a titer of 3,000, one had a titer of 7,000, and the last one had a titer of 22,000!
So, the 8 Pfizer standardized Balb/c mice, quite identical and reacting identically at producing Wuhan antibodies, reacted WILDLY DIFFERENTLY when producing Ba5 antibodies!!! One of them had an immune reaction producing 300 antibody titers, while another similar mouse produced 73 times more antibodies, or 22,000 titers!
Did the mouse who got a 73 times greater immune reaction, feel sicker? Did the mouse who got a 73 times lower reaction, get no protection from Ba.5 variant? Pfizer is not sharing that.
Ba.5 Booster is Dangerous for People
Think for a second about what would happen if these were not mice, but people. Adam would get the Ba.5 booster and develop X amount of antibodies. Whereas, his counterpart Zack would get the same shot, but produce 73X, or 73 times more antibodies!So, Zack would have 73 times more intense, severe, or however you want to call it, reaction compared to Adam!
Would Zack, with his 73 times greater reaction to the same concoction, be much more likely to die of myocarditis? Would Adam remain completely unprotected due to his 73 times lower reaction?
We have no idea!
Nobody has any idea about it: me, you, Pfizer, or the FDA.
But we are giving 171,000,000 doses of this inconsistent concoction to the American people based on this single-page 8-mouse data that nobody even bothered to look at closely.
Of the 171,000,000 future doses distributed, roughly 1/8 of them, or the highest-reacting 21,375,000 people, would have 73 times more severe and intense immune reaction than the bottom, lowest-reacting 21,375,000 people.
Boost Pope
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Relax, it's ok. The young people have learned how to use technology. Have some tea.
More relevantly:
In March of this very year, Star Trek: Picard season 2 episode 2 showed us this dystopian hellscape:
I *think* that the writers intended that more as a warning than a suggestion.
More relevantly:
In March of this very year, Star Trek: Picard season 2 episode 2 showed us this dystopian hellscape:
I *think* that the writers intended that more as a warning than a suggestion.
Everything about that speech last night was just bizarre.
Like, if we weren't receiving a direct feed of it straight from the DC bureau, I'd have thought maybe it was a very clever deepfake by The Babylon Bee or something.
I mean, did anyone here watch Season 2 of Picard?
Anyway, in post-Soviet Russia:
https://twitter.com/loweringthebar/s...11180272308225
Like, if we weren't receiving a direct feed of it straight from the DC bureau, I'd have thought maybe it was a very clever deepfake by The Babylon Bee or something.
I mean, did anyone here watch Season 2 of Picard?
Anyway, in post-Soviet Russia:
https://twitter.com/loweringthebar/s...11180272308225
Next, what's more prevalent; Putin jokes about oligarchs falling out of hospital windows or Hillary Clinton jokes about her enemies committing "suicide?"
It's only a matter of time till one kicks the other out. Maybe this time we can actually stop the big companies, big government, and foreign governments from messing with us.
Moderator
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A national divorce won't be necessary if we stop trying to force 330 million people to fit into a single mold. The Constitution was designed to allow people to move to other jurisdictions within the union that better reflected their values. It allowed for local and regional differences in values on many topics. It allowed for areas to exist with more or less freedom, more or less structure. We are trying to force a one-size-fits-all government over a wildly diverse country instead of leaving the policies in the hands of the people themselves.
People need to stop attempting to make their neighbors conform to some ideal they have dreamed up. Let your neighbor choose for himself what god he will serve, what medical procedures he wants to buy, what drugs or medicines to take, what car he wants to buy, what retirement scheme he wants or doesn't. "Central planning" that assumes the technocrat at the bureaucracy knows better what you need than you do is arrogant and un-American. Give the people liberty to pursue their own happiness as they wish, unimpeded by their government and its tentacles. Let them succeed or fail by their own choices rather than mandating group failure be thrust upon them.
People need to stop attempting to make their neighbors conform to some ideal they have dreamed up. Let your neighbor choose for himself what god he will serve, what medical procedures he wants to buy, what drugs or medicines to take, what car he wants to buy, what retirement scheme he wants or doesn't. "Central planning" that assumes the technocrat at the bureaucracy knows better what you need than you do is arrogant and un-American. Give the people liberty to pursue their own happiness as they wish, unimpeded by their government and its tentacles. Let them succeed or fail by their own choices rather than mandating group failure be thrust upon them.
Retired Mech Design Engr
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This is not the whole picture. If one goes back even further in time, what we see on the right is basically what Crimea looked like before Ukraine started supplying it with water via a canal completed in 1975. The water was shut off in 2014.
I agree with everything you have to say but would like to opine that failure by your own choice shouldn't be the responsibility of gov't to get you out of. This is just as important, if not more important, for businesses than the individual. I mean, if you don't learn from your mistakes, what's stopping you from committing them again.
It took this country many decades to repeat October 1929 but not 2008, apparently.
It took this country many decades to repeat October 1929 but not 2008, apparently.